Quick Answer: What Happens If Chloramphenicol Is Not Refrigerated?

What are the side effect of chloramphenicol?

Common side effects of chloramphenicol include:not enough red blood cells produced (aplastic anemia)bone marrow suppression.diarrhea.inflammation of the small intestine and the colon (enterocolitis)accumulation of chloramphenicol especially in newborns (gray syndrome)headache.nausea.nightmares.More items….

What happens if you touch chloramphenicol?

PRECAUTION FOR HUMANS: Chloramphenicol can cause permanent damage to the bone marrow in about 1 in 10,000 people. For these people, even skin contact can cause permanent damage.

How long can I use chloramphenicol?

Do not use them for more than 5 days, unless your doctor tells you to. This is because your eyes can become more sensitive or you could get another eye infection. Eye ointment – use the ointment until the eye appears normal and for 2 days afterwards. Do not use it for more than a week, unless your doctor tells you to.

How do you store chloramphenicol?

How to store chloramphenicol eye preparationsKeep all medicines out of the reach and sight of children.Chloramphenicol eye drops (including single-use units) must be kept in a fridge (2°C to 8°C).Chloramphenicol eye ointment should be stored in a cool, dry place, away from direct heat and light.More items…•

Why chloramphenicol is banned?

The Committee concluded that the compound is genotoxic, which means it could cause genetic damages and possibly lead to cancer. Chloramphenicol is also known to cause an extremely serious disease in people called “aplastic anemia”.

Can you use too much chloramphenicol?

If you use more chloramphenicol than you should If you accidently apply too much drops, you should wash your eye with plenty of water, if any painful symptoms continue after this, you should tell your doctor immediately.

What type of bacteria does chloramphenicol kill?

Chloramphenicol, antibiotic drug once commonly used in the treatment of infections caused by various bacteria, including those in the genera Rickettsia and Mycoplasma.

Can chloramphenicol make eye worse?

Temporary blurred vision, burning, stinging, or redness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Tell your doctor right away if any of these unlikely but serious side effects occur: vision changes/problems. A very serious allergic reaction to this drug is rare.

What does chloramphenicol do to bacteria?

Chloramphenicol is bacteriostatic but may be bactericidal in high concentrations or when used against highly susceptible organisms. Chloramphenicol stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis.

What infections does chloramphenicol treat?

Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ointment to treat conjunctivitis. By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever.

How long can chloramphenicol be left out of the fridge?

Eye drops can be kept in a cupboard for up to 7 days but it is better to keep them in a fridge. Make sure that the medicine doesn’t freeze. The drops should be taken out of the fridge 2 hours before using them, so that they do not sting.

Is chloramphenicol a steroid?

GENERIC NAME: CHLORAMPHENICOL/HYDROCORTISONE – EYE-EAR OINTMENT (klor-am-FEN-eh-coal/hi-dro-KOR-tih-sown) USES: This medication contains an antibiotic that helps prevent or treat an infection and a steroid which reduces inflammation. It is used in the treatment of various eye (ophthalmic) or ear (otic) conditions.